3-Pyridinecarboxamide, 5-(1-methyl-1H-pyrazol-4-yl)-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]-
CSF1R-IN-1
CAS: 2095849-04-8
Molecular Formula: C25H20F3N5O2
3-Pyridinecarboxamide, 5-(1-methyl-1H-pyrazol-4-yl)-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]- - Names and Identifiers
3-Pyridinecarboxamide, 5-(1-methyl-1H-pyrazol-4-yl)-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]- - Physico-chemical Properties
| Molecular Formula | C25H20F3N5O2 |
| Molar Mass | 479.45 |
| Storage Condition | -20℃ |
| In vitro study | CSF1R is thought to play an important role in recruitment and differentiation of tumor-associated macrophages (TAMs). CSF1R-IN-1 (compound 22) shows good intestinal permeability in a Caco2 assay. |
3-Pyridinecarboxamide, 5-(1-methyl-1H-pyrazol-4-yl)-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]- - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.086 ml | 10.429 ml | 20.857 ml |
| 5 mM | 0.417 ml | 2.086 ml | 4.171 ml |
| 10 mM | 0.209 ml | 1.043 ml | 2.086 ml |
| 5 mM | 0.042 ml | 0.209 ml | 0.417 ml |
Last Update：2024-01-02 23:10:35
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